Healthy Blood Vessels: Your blood vessels are lined with a thin layer of cells called the endothelium. Healthy endothelial cells help blood flow smoothly and regulate blood pressure.

 

Chronic inflammation can damage this protective lining, making it easier for cholesterol, immune cells, and other substances to accumulate within arterial walls.

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Plaque develops: Over time, this buildup can form plaque. Researchers now recognize atherosclerosis as not just a cholesterol problem, but an inflammatory disease process. Inflammatory immune cells within plaques can weaken plaque structure and increase the risk of rupture.

 

Plaque ruptures: If a plaque ruptures, it can trigger a blood clot that blocks blood flow to the heart or brain, potentially causing a heart attack or stroke.

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